Some forms of vascular dementia are characterised by a series of minor strokes caused by reduction of or intermittent supply of blood to areas of the brain.

In the heart, treatment for this condition can include stents and bypass surgery. However, surgery to improve the blood supply within the brain is more difficult. This means alternative nutritional approaches are important.

A study on 121 volunteers by Goplan (2014) has shown that supplementation with mixed Vitamin E tocotrienols were found to reduce the number of white brain matter lesions.

The process is thought to be a result of the brain cells being better protected from intermittent lack of blood supply, rather than an increase in blood supply to the cells.

You can access the abstract by following the link: http://stroke.ahajournals.org/content/early/2014/04/03/STROKEAHA.113.004449.short

Over the past few years the hype about ketones has increased, but why?

In the late 1990’s researchers discovered the impairment of glucose metabolism in Alzheimer’s patients¹. Impairment in glucose metabolism reduces the energy available to the brain and, therefore, reduces function.

As research has progressed, the previous findings led to a method capable of determining the severity of the disease by monitored the decline of glucose metabolism². This made the hypo metabolism of glucose a therapeutic target for Alzheimer’s disease.

This is all well and good but how do we build on this?

It was found that when people fast or starve, their fat reserves are converted into natural ketones which can then be used as energy. However, the brain cannot efficiently convert fats to ketones which results in energy starvation. Administered ketones have been found to efficiently supplement glucose supplies to the brain³.

So, if the ketones are provided directly, the brain can use them as an alternative energy source, quenching the starvation and returning the brain to normal function.
This form of therapy can be vitally important in the early stages of dementia.

KetoactiveEnergy provides an MCT shot when you’re on the move, or need a quick boost which your body can convert into Ketone bodies.

1 Impairment of Neocortical Metabolism Predicts Progression in Alzheimer’s Disease. K. Herholz, A. Nordberg, E. Salmon, D. Perani, J. Kessler, R. Mielke, M. Halber, V. Jelic, O. Almkvist, F. Collette, M. Alberoni, A. Kennedy, s. Hasselbalch, F. Fazio, D. Heiss. Dement Geriatr Cogn Disord 10 (1999) 494–504
2 Early detection of Alzheimer’s disease using neuroimaging. L. Mosconi, M. Brys, L. Glodzik-Sobanska, S. De Santi, H. Rusinek, M. J. de Leon. Experimental Gerontology 42 (2007) 129–138
3 Ketone Bodies as a Therapeutic for Alzheimer’s Disease. S T. Henderson. Neurotherapeutics: The Journal of the American Society for Experimental NeuroTherapeutics 5 (2008) 470 – 480

1: The structure of all cell membranes

– The long chain Omega 3 DHA (and omega 6 AA) increase membrane fluidity, essential for optimum cell signalling.

2: The function of the brain and nerves

– 6-10% of the dry mass of the brain, should be DHA. Levels reduce with age and some research suggests this is a contributory factory in the development of Alzheimer disease.

– DHA is concentrated in nerve junctions, where chemical signals between nerves are passed.

– The concentration of neurotransmitters dopamine, serotonin and noradrenalin are influenced by Omega 3 DHA status.

KetoactiveMind provides 420mg of DHA, which contributes to normal brain function.